General Cell Based Assays
Eurofins Discoverx PathHunter Human EDNRB Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human EDNRB Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDNRB (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2C(VNV) (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR2C(VNV) (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human p53 (TP53) Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human p53 (TP53) Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure p53 DNA damage pathway activation via nuclear translocation of p53. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Human AQ STING Binding Kit, 100,000 Assay Points
HTRF Human AQ STING Binding Kit, 100,000 Assay Points
Eurofins Discoverx PathHunter CXCR5 Bioassay Kit, 2-Plate. (93-0514Y2-00063)
The PathHunter CXCR5 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. CXCL13) based activation of CXCR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR5 and EA-tagged β-Arrestin-2. Activation of CXCR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.